Recent Publications

Tian L, Jarrah M, Chu Y, Herz H, Xu Y, Tang Y, Yuan J, Mokadem M*. Toll-like Receptor 4 Differentially Modulates Cardiac Function in Response to Chronic Exposure to High-Fat Diet and Pressure Overload. Nutrients, 2023, 15, 5139. 

Jarrah M, Mokadem M*. Pharmaco-endoscopic Therapy for Weight Regain Post-Gastric Bypass: A Case Report. J Surg Case Rep. 2023 Feb 28 ;2023(2):rjad075.

Prakash S, Saavedra R, Lehman R, Mokadem M*. Candy cane syndrome presenting with refractory heartburn 15 years after Roux-en-Y bypass. J Surg Case Rep. 2023 Mar 18;2023(3):rjad130.

Ye Y, Abu El Haija M, Obeid R, Herz H, Tian L, Linden B, Chu Y, Guo DF, Levine DC, Jonathan C, Rahmouni K, Bass J, Mokadem M*. Gastric bypass alters diurnal feeding behavior and reprograms hepatic clock to regulate endogenous glucose flux. JCI Insights. 2023 Mar 22;8(6):e166618. doi: 10.1172/jci.insight.

Herz H, Song Y, Ye Y, Tian L, Linden B, Abu El Haija M, Chu Y, Grobe JL, Lengeling RW, Mokadem M*. NSAID-Induced Enteropathy Affects Regulation of Hepatic Glucose Production by Decreasing GLP-1 Secretion. Nutrients. 2022; 14(1):120. 

Xi J, Ye Y, Mokadem M, Yuan J, Kawai M. The effect of gender and obesity in modulating cross-bridge function in cardiac muscle fibers. J Muscle Res Cell Motil. 2022 Aug 22. doi: 10.1007/s10974-022-09627-z. Epub ahead of print.

Calderon G, Gonzalez-Izundegui D, Shan KL, Garcia-Valencia OA, Cifuentes L, Campos A, Collazo-Clavell ML, Shah M, Hurley DL, Abu Lebdeh HS, Sharma M, Schmitz K, Clark MM, Grothe K, Mundi MS, Camilleri M, Abu Dayyeh BK, Hurtado Andrade MD, Mokadem M*, Acosta A*. Effectiveness of anti-obesity medications approved for long-term use in a multidisciplinary weight management program: a multi-center clinical experience. Int J Obes (Lond). 2022 Mar;46(3):555-563. doi: 10.1038/s41366-021-01019-6. Epub 2021 Nov 22.

Khashab M, Mokadem M, DeWitt J, Emerson R, Sherman S, LeBlanc J, McHenry L, Al-Rashdan A, Al-Haddad M. Endoscopic ultrasound-guided fine-needle aspiration with or without flow cytometry for the diagnosis of primary pancreatic lymphoma - a case series. Endoscopy. 2010 Mar;42(3):228-31. doi: 10.1055/s-0029-1243859. Epub 2010 Jan 25.

Abu El Haija M, Ye Y, Chu Y, Herz H, Linden B, Shahi SK, Zarei K, Mangalam AK, Mcelroy SJ, Mokadem M*. Toll-like receptor 4 and myeloid differentiation factor 88 are required for gastric bypass-induced metabolic effects. Surg Obes Relat Dis. 2021 Dec;17(12):1996-2006. doi: 10.1016/j.soard.2021.07.019. Epub 2021 Aug 2. PMID: 34462225.

Chu Y, Tian L, Herz H, Linden B, Morgan DA, Naber MC, Potthoff M, Rahmouni K, Mokadem M*. Gastric Bypass Sensitizes Sympathetic and Thermogenic Activity of Brown Adipose Tissue to Cold Exposure. Obes Surg. 2021 Jul 15. doi: 10.1007/s11695-021-05560-1. Epub ahead of print. PMID: 34264434.

Hasan Y, Ali A, Sayed AE, Levin A, Gerke H, Jhun HY, Mokadem M, Abiad RE, Jesudoss R, Polyak S, Sahar N. Direct endoscopic placement of percutaneous endoscopic gastrostomies with jejunal extension tubes (PEG-J) using ultra-thin endoscopes - long-term outcomes from a U.S. tertiary referral center. Surg Endosc. 2021 Oct 12. doi: 10.1007/s00464-021-08757-8. Epub ahead of print. PMID: 34642797.

An Z, Wang H, Mokadem M*. Role of the Autonomic Nervous System in Mechanism of Energy and Glucose Regulation Post Bariatric Surgery. Front Neurosci. 2021 Nov 23;15:770690. doi: 10.3389/fnins.2021.770690. PMID: 34887725; PMCID: PMC8649921.

Riedl RA, Burnett CML, Pearson NA, Reho JJ, Mokadem M, Edwards RA, Kindel TL, Kirby JR, Grobe JL. Gut Microbiota Represent a Major Thermogenic Biomass. Function (Oxf). 2021 Apr 15;2(3): zqab019. doi: 10.1093/function/zqab019. PMID: 33939772; PMCID: PMC8055641.

Cedernaes J, Huang W, Moynihan Ramsey K, Cheng L, Marcheva B, Omura C, Kobayashi Y, Bien Peek C, Levine DC, Bradfield CA, Wang XA, Takahashi JS, Mokadem M, Ahima RS, Bass J. Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron. Cell Metab. 2019 Feb 18. pii: S1550-4131(19)30063-4. doi: 10.1016/j.cmet.2019.01.023.

Winward J, Lyckholm L, Brown SM, Mokadem M*. Case of relapsing sulfasalazine-induced hypersensitivity syndrome upon re-exposure. BMJ Case Rep. 2020 Sep 15;13(9):e235803. doi: 10.1136/bcr-2020-235803. PMID: 32933910; PMCID: PMC7493089.

Ye Y, Abu El Haija M, Morgan DA, Guo D, Song Y, Frank A, Tian L, Riedl RA, Burnett CML, Gao Z, Zhu Z, Shahi SK, Zarei K, Couvelard A, Poté N, Ribeiro-Parenti L, Bado A, Noureddine L, Bellizzi A, Kievit P, Mangalam AK, Zingman LV, Le Gall M, Grobe JL, Kaplan LM, Clegg D, Rahmouni K, Mokadem M*. Endocannabinoid Receptor-1 and Sympathetic Nervous System Mediate the Beneficial Metabolic Effects of Gastric Bypass. Cell Rep. 2020 Oct 27;33(4):108270. doi: 10.1016/j.celrep.2020.108270.

Mokadem M, Noureddine L, Howard T, McHenry L, Sherman S, Fogel EL, Watkins JL, Lehman GA. Total pancreatectomy with islet cell transplantation vs intrathecal narcotic pump infusion for pain control in chronic pancreatitis. World J Gastroenterol. 2016 Apr 28;22(16):4160-7. doi: 10.3748/wjg.v22.i16.4160.

Mokadem M, Zechner JF, Uchida A, Aguirre V. Leptin Is Required for Glucose Homeostasis after Roux-en-Y Gastric Bypass in Mice. PLoS One. 2015 Oct 7;10(10):e0139960. doi: 10.1371/journal.pone.0139960. eCollection 2015.

Li H, Chan L, Bartuzi P, Melton SD, Weber A, Ben-Shlomo S, Varol C, Raetz M, Mao X, Starokadomskyy P, van Sommeren S, Mokadem M, Schneider H, Weisberg R, Westra HJ, Esko T, Metspalu A, Kumar V, Faubion WA, Yarovinsky F, Hofker M, Wijmenga C, Kracht M, Franke L, Aguirre V, Weersma RK, Gluck N, van de Sluis B, Burstein E. Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer.
Gastroenterology. 2014 Jul;147(1):184-195.e3. doi: 10.1053/j.gastro.2014.04.007. Epub 2014 Apr 13.

Mokadem M, Zechner JF, Margolskee RF, Drucker DJ, Aguirre V. Effects of Roux-en-Y gastric bypass on energy and glucose homeostasis are preserved in two mouse models of functional glucagon-like peptide-1 deficiency. Mol Metab. 2013 Dec 11;3(2):191-201. doi: 10.1016/j.molmet.2013.11.010. eCollection 2014 Apr.

Barada K, Bitar A, Mokadem MA, Hashash JG, Green P. Celiac disease in Middle Eastern and North African countries: a new burden? World J Gastroenterol. 2010 Mar 28;16(12):1449-57. Review.